Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...
Abstract: Spatial transcriptomics (ST) clustering identifies distinct spatial domains within tissues and elucidates cellular interactions. While this approach has advanced human understanding of ...
Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...
DeepSpot: Leveraging Spatial Context for Enhanced Spatial Transcriptomics Prediction from H&E Images
Do you want to generate spatial transcriptomics data using your H&E images? We introduce DeepSpot, a novel deep-learning model that predicts spatial transcriptomics from H&E images. DeepSpot employs a ...
New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...
This manuscript by Kaur et al. identifies differential gene expression in distinct cell populations, specifically myeloid and lymphoid cells, following short-term exposure to e-cigarette aerosols with ...
Foster City, Calif. | January 27, 2026 — Signios Bio today announced the launch of a new grant program supporting innovative spatial transcriptomics research using the 10x Genomics Xenium 5K Spatial ...
Laboratory equipment developer SPT Labtech has collaborated with biotechnology company Pacific Biosciences (PacBio) to automate PacBio’s Kinnex full-length RNA-seq library preparation on SPT’s firefly ...
Transcriptomics represents a critical discipline in cancer research, enabling comprehensive mapping of gene expression profiles and the identification of fusion genes implicated in tumor development.
Biotechnology company Alithea Genomics has collaborated with automated instrumentation designer SPT Labtech to develop an automated solution for single-cell transcriptomics. “This collaboration ...
Vascular smooth muscle cells and pericytes are mural cells that maintain the integrity and support the function of blood vessels. The molecular mechanism underlying the specification of pericytes and ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
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