In recent decades, peptide research has expanded beyond classical endocrine and paracrine paradigms toward a more nuanced understanding of short peptides as informational entities with the potential ...
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and are now increasingly recognized as conditions with a strong ...
A newly proposed model suggests cancer cells may resist treatment not just through genetic mutations, but by dynamically ...
Dr. Georg Winter explores how chemical neomorphs can give proteins new functions by reshaping their cellular interactions, ...
Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, ...
Microglia, being the resident immunological sentinels of the central nervous system (CNS), play a critical role in both the pathogenesis and progression of CNS health and disease. In sepsis-associated ...
St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...
Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators have defined a new genetic disease marked by premature aging and deficits in brain function.
As cell therapy advances toward clinical reality, iPSC-derived cellular products, in vivo reprogramming strategies, and manufacturing-ready reagent platforms are reshaping regenerative medicine and ...
“How old would you like to be when you die?” That’s the question my primary care physician asked during my routine physical. It’s a complex question, one without a right answer. As long as possible, ...
“Alexander Meissner’s work has fundamentally advanced our understanding of epigenetic regulation and cellular reprogramming,” said ISSCR President Hideyuki Okano. “Equally important is his dedication ...