Professor Pan Xu's research group at Southeast University reported a photocatalytic hydrogen atom transfer (HAT) strategy, successfully achieving the deconjugated olefin isomerization reaction of ...
Disaccharides play a crucial role in protecting biological membranes from desiccation. Previous studies suggest that disaccharides with α,α-(1-1) glycosidic linkages, which adopt a clamshell ...
Efficacy and safety of the DLL3/CD3 T-cell engager obrixtamig in patients with extrapulmonary neuroendocrine carcinomas with high or low DLL3 expression: Results from an ongoing phase I trial.
The growing burden of metabolic disorders manifested by hypertension, type 2 diabetes mellitus, hyperlipidemia, obesity and non-alcoholic fatty liver disease presents a significant global health ...
This fundamental work demonstrates that ABHD6 regulates AMPAR gating kinetics in a TARP γ-2-dependent manner. The evidence in this study is compelling. This study will be of interest to readers in the ...
First-in-human, phase 1/2 study of GSK4524101, an oral DNApolymerase theta inhibitor (POLQi), alone or combined with the poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) niraparib in adults with ...
The strongest force in the universe is called, aptly, the strong force. We never get to witness its fearsome power because it works only across subatomic distances, where it binds quarks together ...
Janus kinase (JAK) inhibitors, including baricitinib, block cytokine signaling and are effective disease-modifying treatments for several autoimmune diseases. Whether baricitinib preserves β-cell ...
Teplizumab, a humanized monoclonal antibody to CD3 on T cells, is approved by the Food and Drug Administration to delay the onset of clinical type 1 diabetes (stage 3) in patients 8 years of age or ...
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