From single DNA letter swaps to hidden non-coding tweaks, mutations can rewire how our bodies work—sometimes in life-changing ways. Scientists are uncovering how these changes influence protein ...

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

A study by IRB Barcelona reveals that transfer RNA (tRNA) genes accumulate mutations at a frequency up to nine times higher ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.

Inocras and the Broad Institute analyzed 8,000+ TCGA cancer genomes to uncover new drivers and create a harmonized dataset ...

A study finds tRNA genes are mutation hotspots that alter protein synthesis, leading to proteome instability, contributing to ...

With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), Shira Weingarten-Gabbay and colleagues identified more than 4000 open reading frames (ORFs) across 679 ...

Late in 2025, we covered the development of an AI system called Evo that was trained on massive numbers of bacterial genomes. So many that, when prompted with sequences from a cluster of related genes ...

Neuronal specification, expansion and differentiation are tightly regulated by the concerted actions of transcription and chromatin modifying factors that are recruited to regulatory elements in the ...