The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

Cynomolgus monkeys (Macaca fascicularis) and common marmosets (Callithrix jacchus) serve as critical models for drug metabolism studies due to their close genetic and physiological parallels with ...

Cinnamon is one of the oldest and most commonly used spices in the world, but a new study from the National Center for Natural Products Research indicates a compound in it could interfere with some ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

A new combination of existing drugs reduces the size of cancerous tumors much more effectively than current treatments. A new drug lead shows promise that it could reduce the size of cancerous tumors ...

This article is based on a poster originally authored by Daniel A. Barr, Mario Öeren, Peter A. Hunt, Jonathan D. Tyzack, Tomáš Chrien, Tamsin E. Mansley and Matthew D. Segall, which was presented at ...

The skin over a mouse’s shoulders warmed up after a dozen days on tirzepatide. That heat map, taken with an infrared camera, pointed to a familiar patch of tissue between the shoulder blades: brown ...

New research explains the role of genes and other health factors.

Scientists are experimenting with a novel approach to treating Alzheimer's disease in mice. They're using a drug that helps the brain make energy. NPR's Jon Hamilton says in a mouse, at least, the ...

A common lab fish is helping autism research take a more targeted turn The fish are only a few days old, barely beyond the larval stage, and yet their movements can hint at something much larger. A ...